Bolivia is a country with a mining tradition, since colonial times, large quantities of mineral were extracted from Potosí that generated important economic income for national and transnational mining companies and to a lesser extent for the General Treasury of the Nation through royalties and taxes. The above suggests economic-social progress in the mining areas and in the department, however, this is not the case. Given this, this study focuses on analyzing the exploitation of white gold (lithium) in Bolivia in the past and its future projection from responsible business management. Methodologically, it is a study focused on the quantitative approach with a field, non-experimental and transectional design. The findings suggest that the exploitation of lithium is a great opportunity to obtain economic income from royalties and taxes, since Bolivia has the largest lithium reserves in the world with 23 million certified tons. On the other hand, direct lithium extraction technology reduces time and costs, generating greater efficiency and less environmental impact with ultra-treated and reused water. Therefore, it is concluded that a promising future is foreseen in terms of exploitation and export of lithium carbonate, guaranteeing greater income in less time than traditional mining, and at the same time from sustainable business management, local social development of the areas where it is does mining